At a glance

QUICK SUMMARY

01 Type of medicine

Topical Antiviral Cream

02 Generic

Yes, generic versions available

03 Active ingredient

Aciclovir (Acyclovir) 5% w/w

04 Effective within

Varies; typically within days

05 Works by

Inhibiting HSV-1 replication

06 Side effects

Mild burning, itching, redness

Medication details

Description

Zovirax Cold Sore Cream

Zovirax Cold Sore Cream is a topical antiviral for cold sores, also called fever blisters, applied to the lips and face. The active ingredient is aciclovir, and the cream reduces the severity and duration of an outbreak along with the associated discomfort, itching and burning.

How it works

Cold sores are caused by the herpes simplex virus, which lives dormant in a nerve near the lip and reactivates at times of stress, illness, tiredness or strong sunlight. Aciclovir blocks the enzyme the virus uses to copy its own DNA, so it cannot multiply and spread through the surrounding cells. Because it stops replication rather than killing what has already formed, timing is everything.

How to use it

Apply at the first sign of an outbreak, which is the tingling or itching phase before anything is visible, since that is when the virus is replicating fastest and when treatment makes the greatest difference. Dab it onto the affected area as directed on the pack and wash your hands before and after. Applied during the prodromal phase it can sometimes prevent a full cold sore developing; applied once the blister has crusted it does far less.

Who it is for

It is for adults and children as stated on the pack with recurrent cold sores on the lips and face. It is not for use inside the mouth, in the eyes, or on the genital area, and not for anyone sensitive to aciclovir.

Safety and when to get advice

Mild stinging, burning or dryness at the site can occur. See a clinician if cold sores are very frequent or unusually severe, if the sore has not healed after around ten days, if it is spreading, or if it is near the eye, which needs prompt attention. Anyone with a weakened immune system or eczema should seek advice early, since the virus can spread more widely. Avoid kissing and sharing towels, cups or lip products during an outbreak, and do not pick the sore. Our UK pharmacy team can answer questions about this product before you buy.

Common questions

When should I apply it?
At the very first tingle, before the blister appears. That is when it works best.

Will it work once the blister has formed?
It can still help, but much less than treatment started at the tingling stage.

Why do cold sores keep coming back?
The virus stays dormant in a nerve and reactivates with stress, illness, tiredness or strong sunlight. A lip balm with SPF helps some people.

Always read the patient information leaflet supplied with the pack before use.

Directions

To ensure effective and safe use of Zovirax Cold Sore Cream, follow these step-by-step directions:
Clean Hands: Before application, wash your hands thoroughly to maintain good hygiene.
Apply Early: Start using Zovirax Cold Sore Cream at the earliest sign of a cold sore (tingling, itching, or burning sensation). The sooner you apply it, the more effective it may be.
Dosing Frequency: Apply a small amount of Zovirax Cold Sore Cream (about the size of a small pea) to the affected area on or around the lips. This is typically done five times a day, approximately every 4 hours, unless directed otherwise by a healthcare provider.
Apply with a Clean Finger or Cotton Swab: Use a clean fingertip or a cotton swab to apply the cream. Avoid using your lips to spread the cream.
Wash Hands After Application: After applying the cream, wash your hands thoroughly to prevent spreading the virus to other areas of your body.
Continue Treatment: Continue using Zovirax Cold Sore Cream for a minimum of 4 days, even if the cold sore has healed. This ensures that the virus is fully suppressed.
Always read and adhere to the instructions on the product label for specific dosing and usage guidelines.

Ingredients

Zovirax Cold Sore Cream contains the active ingredient aciclovir (acyclovir) at a concentration of 5% w/w. Aciclovir is an antiviral medication that works by inhibiting the replication of the herpes simplex virus, thereby reducing the duration and severity of cold sore outbreaks.

Side Effects

Zovirax Cold Sore Cream is generally well-tolerated, but like any medication, it may cause side effects in some individuals. Common side effects associated with this product may include:
Mild burning or stinging sensation at the application site
Dry or cracked lips
Itching or redness
These side effects are typically mild and transient. If any side effects persist or worsen, discontinue use and consult a healthcare provider.

Warnings

Before using Zovirax Cold Sore Cream, consider the following important warnings and precautions:
Allergies: If you are allergic to aciclovir or any other ingredients in Zovirax Cold Sore Cream, do not use the product.
Eye Contact: Avoid getting the cream in your eyes. If accidental contact occurs, rinse your eyes thoroughly with water and seek medical attention if irritation persists.
Pregnancy and Breastfeeding: Pregnant or breastfeeding individuals should seek advice from a healthcare professional before using this product.
Use in Children: Zovirax Cold Sore Cream is generally considered safe for children over the age of 12. For younger children, consult a healthcare provider.
Use as Directed: Use Zovirax Cold Sore Cream as directed on the product label or as advised by a healthcare provider. Do not exceed the recommended dose or frequency of application.
Not a Preventive Measure: Zovirax Cold Sore Cream is not intended to prevent the transmission of HSV-1 to others. It is designed for the treatment of active cold sores.

Medically reviewed and published

  • This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on Oct 5, 2023, 2:45 pm

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FAQs

Please read our FAQs page to find out more.

How does Zovirax Cream work?

Zovirax Cream contains aciclovir (acyclovir), an antiviral medication. It works by inhibiting the replication of the herpes simplex virus, reducing the duration and severity of cold sore outbreaks.

Can I use Zovirax Cream to prevent cold sores?

Zovirax Cream is designed for the treatment of active cold sores and is not meant for preventive use. It should be applied at the first sign of a cold sore outbreak.

What is the recommended age for using Zovirax Cream?

Zovirax Cream is generally considered safe for individuals aged 12 and older. Consult a healthcare provider for guidance if you have concerns about its use in younger children.

Can Zovirax Cream be used on genital herpes or other herpes infections?

Zovirax Cream is specifically formulated for the treatment of cold sores caused by herpes simplex virus type 1 (HSV-1). It is not intended for use on genital herpes or other herpes infections. Consult a healthcare provider for appropriate treatment options for genital herpes.

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