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At a glance

QUICK SUMMARY

01 Type of medicine

Hormone Replacement Therapy (HRT)

02 Generic
03 Active ingredient

Progesterone 100mg

04 Effective within

Varies by Individual

05 Works by

Supplementing Progesterone Levels

06 Side effects

Stomach pain, Nausea, Tiredness, Headache, Vaginal bleeding, Intense itching

MEDICATION DETAILS

Description

Utrogestan 100mg Capsules

Utrogestan contains progesterone and is taken together with oestrogen as part of hormone replacement therapy, or HRT. As the menopause approaches, levels of oestrogen and progesterone decline, and HRT replaces these hormones to reduce menopausal symptoms. It is a medicine that requires a clinician to assess whether it is suitable for you.

How it works

The progesterone in Utrogestan is body identical, meaning it is structurally the same as the progesterone the body produces. Its role alongside oestrogen is protective. If HRT contains only oestrogen, the lining of the womb can build up unchecked, which causes health problems. Taking Utrogestan with oestrogen sheds or thins that lining and prevents this, which is why it is essential for anyone with a womb who is taking oestrogen.

How to use it

Take the capsules exactly as your clinician has directed, since the regimen differs depending on whether you are taking it continuously or on a cyclical basis. It is usually taken at bedtime, because drowsiness is a recognised effect and is more useful at night than during the day. Do not stop or alter the dose without speaking to your clinician.

Who it is for

It is for women taking oestrogen as part of HRT who still have a womb. It is not suitable where there is unexplained vaginal bleeding, a history of breast or other hormone dependent cancer, a history of blood clots, or certain liver conditions. It contains peanut oil, so it is not suitable for anyone allergic to peanuts or soya.

Safety and when to get advice

Drowsiness, dizziness, headache, breast tenderness and changes to bleeding patterns are reported. See a clinician promptly for any unexpected or heavy vaginal bleeding, and seek urgent help for pain or swelling in a leg, chest pain, sudden breathlessness, a severe headache, or weakness or numbness on one side. Keep up routine breast and cervical screening invitations, and attend your HRT reviews. Our UK pharmacy team can answer questions about this product before you buy.

Common questions

Why do I need progesterone as well as oestrogen?
To protect the lining of the womb, which oestrogen alone would cause to build up.

Why take it at bedtime?
Drowsiness is a recognised effect, so taking it at night is generally more convenient.

Does it contain peanut?
Yes. It contains peanut oil and is not suitable if you are allergic to peanuts or soya.

Always read the patient information leaflet supplied with the pack before use.

Directions

Take ONE(100mg) capsule at bedtime from Day 1 to Day 25 of each therapeutic cycle

Ingredients

Each capsule contains 100mg progesterone.
The other ingredients in the capsule shell are gelatin, glycerol, titanium dioxide and purified water.

Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Common side effects may include:
• Bloating of the stomach
• Depression
• Breast tenderness
• Hot flashes
• Vaginal discharge
• Joint pain
• Urinary problems

Warnings

You may have some bleeding at the end of each month, rather like a period. If you experience any side effects, talk to your doctor or pharmacist.

Medically reviewed and published

  • This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on

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FAQs

Please read our FAQs page to find out more.

Why should I take Utrogestan at bedtime?

Progesterone can cause drowsiness and dizziness. Taking it at bedtime means these effects happen while you are asleep rather than during the day. It should also be taken on an empty stomach, as food can affect how it is absorbed.

Is the bleeding at the end of each cycle normal?

Yes. A few days of withdrawal bleeding after each course of Utrogestan is expected and is a sign that the womb lining is shedding as intended. This is part of how it protects the womb when you are taking oestrogen. If you have unexpected or heavy bleeding, speak to a clinician.

Is Utrogestan a contraceptive?

No. Although it contains progesterone, Utrogestan is designed as part of HRT and does not work as a contraceptive. If you need contraception, discuss this separately with our pharmacy team at info@rightangled.com.

Do I need to tell my surgeon if I am having an operation?

Yes. You may need to stop HRT about four to six weeks before planned surgery to reduce the risk of blood clots. Tell your surgeon and our pharmacy team so the timing can be planned. Your clinician will let you know when it is safe to restart.

We are here to help 👋

For assistance, please contact our customer service at info@rightangled.com. We are available Monday to Friday from 8 am to 5 pm. For urgent issues, please do not use this email. Instead, call 111, or dial 999 in case of an emergency.

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