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At a glance

QUICK SUMMARY

01 Type of medicine

Migraine headache treatment (Triptan)

02 Generic

Yes

03 Active ingredient

Sumatriptan (as sumatriptan succinate)

04 Effective within

As soon as possible after onset of migraine attack

05 Works by

Narrowing blood vessels to relieve migraine symptoms

06 Side effects

Chest discomfort, unusual sensations, nausea, vomiting, tiredness, drowsiness, dizziness, weakness, hot flushes, temporary increase in blood pressure

MEDICATION DETAILS

Description

Sumatriptan 50mg Tablets

Sumatriptan 50mg is used to treat acute attacks of migraine and, in some cases, cluster headache. It is taken once an attack has begun and eases the throbbing pain along with the nausea and sensitivity to light and sound that accompany it. It is a medicine that requires a clinician to assess whether it is suitable for you, and it is not a preventative treatment.

How it works

Sumatriptan belongs to the triptan group and acts on serotonin receptors in the blood vessels around the brain. It narrows those vessels, which dilate during an attack, and blocks the release of the inflammatory substances that amplify the pain signal. It addresses the attack that is underway and has no effect on how often attacks happen, which is why it should not be taken routinely.

How to use it

Take one tablet with water as soon as the headache phase starts, rather than during an aura if you get one. If the headache responds and then returns, a further dose may be taken after the stated interval, but if the first dose has no effect at all, a second for the same attack will not help either. Observe the maximum in 24 hours, and resting in a dark quiet room alongside often makes a noticeable difference.

Who it is for

It is for adults with a confirmed migraine diagnosis where a clinician has agreed it is appropriate. It is not suitable for anyone with coronary heart disease, a history of heart attack or stroke, uncontrolled high blood pressure or significant peripheral vascular disease, and it must not be combined with an MAOI or taken within two weeks of stopping one.

Safety and when to get advice

Tingling, dizziness, drowsiness and a sensation of heaviness, tightness or warmth in the chest, neck or jaw are commonly reported. Seek urgent medical help for significant chest pain or tightness, breathlessness, or stroke symptoms such as weakness, numbness or difficulty speaking. Contact a clinician if your headache pattern changes, if it is the worst you have ever had, if it comes with fever, a stiff neck or confusion, or if you are using acute treatment on more than about 10 days a month, since that itself causes headache. Our UK pharmacy team can answer questions about this product before you buy.

Common questions

How is this different from the pharmacy version?
The active ingredient is the same. Pharmacy supply has narrower criteria; this is supplied after a clinician assessment.

Can I take it during the aura?
Take it when the headache begins rather than during the aura phase.

Does it prevent migraines?
No. It treats an attack in progress. Prevention is a separate conversation with a clinician.

Always read the patient information leaflet supplied with the pack before use.

Directions

Always follow your doctor's or pharmacist's instructions on how to take Sumatriptan.
The recommended dose is typically 50 mg, with some patients needing 100 mg in the event of a migraine attack.
Take the tablet with water as soon as possible after the onset of the migraine attack.
Do not chew or crush the tablets.

Ingredients

Each tablet contains either 50 mg or 100 mg of sumatriptan (as sumatriptan succinate).
Other ingredients include croscarmellose sodium (E468), polysorbate 80 (E433), calcium hydrogen phosphate (E450), microcrystalline cellulose (E460), sodium hydrogen carbonate (E500), and magnesium stearate (E470b).

Side Effects

Like all medications, Sumatriptan can cause side effects, although not everyone experiences them. Some of the common side effects include:
Heaviness, pressure, tightness, or pain in the chest or other body parts.
Feeling of unusual sensations, such as numbness, tingling, warmth, or cold.
Nausea, vomiting, tiredness, drowsiness, dizziness, weakness, hot flushes, and temporary increase in blood pressure.
Very rare side effects:
Changes in liver function.
Seizures/fits, tremors, muscle spasm, neck stiffness.
Visual disturbances, heart problems, angina, heart attack.
Pale, blue-tinged skin, pain in extremities due to cold or stress (Raynaud’s phenomenon).
Feeling faint, pain in the lower left side of the stomach, and bloody diarrhea (ischaemic colitis).
Diarrhea, joint pain, anxiety, excessive sweating, difficulty swallowing.
It's important to report any side effects to your doctor or pharmacist. If you experience symptoms like rash, hives, wheezing, swollen eyelids, face or lips, or chest pain, seek medical attention immediately.

Warnings

Do not take Sumatriptan if you are allergic to it or any of its ingredients, have certain heart problems, circulation issues, or have had a stroke.
Inform your doctor if you are using other medications, especially ergotamine, other triptans, SSRIs, SNRIs, MAOIs, or St. John's Wort.
Pregnant or breastfeeding women should consult their doctor before using Sumatriptan.
If you experience chest pain after using Sumatriptan, seek medical help.
Do not exceed the recommended dose of 300 mg in a 24-hour period.

Medically reviewed and published

  • This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on Aug 24, 2023, 3:30 pm

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FAQs

Please read our FAQs page to find out more.

Can Sumatriptan prevent future migraine attacks?

No, Sumatriptan is not meant to prevent future migraine attacks. It is effective only during the course of a migraine attack to provide relief from symptoms.

Can I take Sumatriptan if I'm pregnant or breastfeeding?

Pregnant or breastfeeding women should consult their doctor before using Sumatriptan. Limited information is available regarding its safety during pregnancy.

Can I use Sumatriptan if I have other health conditions?

Inform your doctor if you have heart problems, circulation issues, liver or kidney disease, history of fits, or are taking certain medications like SSRIs, SNRIs, MAOIs, or St. John's Wort. Your doctor will assess the risks and benefits before prescribing Sumatriptan.

Can I use Sumatriptan with other migraine medications?

Certain migraine medications, such as ergotamine and other triptans, should not be used concurrently with Sumatriptan. Consult your doctor before using multiple migraine treatments.

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