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It works by reducing the amount of acid your stomach produces, helping to relieve discomfort and prevent symptoms from returning.
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Omeprazole Tablets [28 tablets]
2-3 minutes online assessment to check your eligibility for a treatment
proton pump inhibitor (PPI). It
Yes
Omeprazole
Omeprazole typically begins reducing stomach acid within 1-2 hours after ingestion, with full therapeutic effects usually seen after 2-3 days of regular use.
It works by reducing the amount of acid your stomach produces, helping to relieve discomfort and prevent symptoms from returning.
Headache, diarrhoea, stomach pain, constipation vomiting and nausea
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Omeprazole Tablets are used for acid related conditions including heartburn, acid reflux, indigestion and stomach ulcers. Omeprazole is a proton pump inhibitor, or PPI, which reduces how much acid the stomach produces. This is the tablet form, which some people find easier to take than a capsule. It is a medicine that requires a clinician to assess whether it is suitable for you.
The lining of the stomach contains pumps that generate acid. A PPI shuts those pumps down at source. That is why it differs from an antacid, which neutralises acid already present and wears off quickly, and from an alginate, which forms a raft to stop acid rising. The trade off is that a PPI builds over several days rather than giving instant relief, so it is taken as a course rather than when symptoms strike.
Swallow the tablet whole with water, usually in the morning before food, exactly as directed. Do not chew or crush it, as it is gastro resistant and needs to pass the stomach intact. Finish the course your clinician has set even once symptoms settle. Alongside it, smaller evening meals, less alcohol and caffeine, and not lying down soon after eating all reduce reflux.
It is for people where a clinician has confirmed a PPI is appropriate. Tell your clinician about liver problems, low magnesium, osteoporosis risk and all other medicines, since omeprazole interacts with several, including clopidogrel, methotrexate and some HIV medicines.
Headache, diarrhoea, constipation, wind and nausea are among the reported effects. Long term use is reviewed because of effects on magnesium, vitamin B12 and bone health. See a doctor promptly for difficulty or pain on swallowing, food sticking, unexplained weight loss, persistent vomiting, vomit resembling coffee grounds or black tarry stools. Seek emergency help for chest pain with breathlessness or sweating. Our UK pharmacy team can answer questions about this product before you buy.
Tablets or capsules?
Both deliver the same medicine in a gastro resistant form. Choice usually comes down to what you find easier to swallow.
How soon will it help?
The effect builds over a few days rather than on the first dose.
Can I stop once I feel better?
Finish the course your clinician set, especially if you are being treated for an ulcer.
Always read the patient information leaflet supplied with the pack before use.
Medically reviewed and published
This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on Apr 11, 2026, 4:00 pm
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Based on your current dose, you could switch to:
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