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Replacing estrogen locally in the vagina to relieve menopausal symptoms
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Gina 10 Micrograms Vaginal Tablets
Vaginal Tablet
No
Estradiol (as estradiol hemihydrate)
Gradual improvement; symptoms may take a few months to improve
Replacing estrogen locally in the vagina to relieve menopausal symptoms
Headache Stomach pain Vaginal bleeding, discharge, or discomfort Nausea Rash Weight increase Hot flush High blood pressure
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Gina is a low dose vaginal estrogen tablet for postmenopausal vaginal symptoms, and was the first postmenopausal hormone replacement therapy made available in the UK without a prescription. It is used for vaginal dryness, itching, soreness and pain during sex, and is supplied from a pharmacy following a short consultation.
After the menopause, falling estrogen levels cause the tissue of the vagina and vulva to become thinner, drier and less elastic, which is what produces the dryness, irritation and discomfort during sex. Gina delivers a very low dose of estradiol directly to that tissue, where it restores thickness, elasticity and natural lubrication. Because the dose is low and applied locally, very little is absorbed into the rest of the body.
Insert one tablet into the vagina using the applicator supplied, following the pack instructions, usually daily at first and then twice weekly for maintenance. Bedtime suits most people. Symptoms generally improve over a few weeks rather than immediately, and continued use is needed to maintain the benefit.
Pharmacy supply is for postmenopausal women aged 50 to 65 who have not had a period for at least a year, following a consultation. It is not suitable where there is unexplained vaginal bleeding, a history of breast or other hormone dependent cancer, a history of blood clots, or certain liver conditions, which is what the consultation checks.
See a clinician promptly for any vaginal bleeding after the menopause, which always needs assessment, and for breast changes, pain or swelling in a leg, chest pain or sudden breathlessness. Contact a clinician if symptoms have not improved after around three months of use, or before continuing beyond the review period stated on the pack. Keep up routine breast screening and cervical screening invitations. Our UK pharmacy team can answer questions about this product.
Is this the same as HRT tablets?
It is a local vaginal estrogen at a very low dose, which treats vaginal symptoms rather than flushes or night sweats.
How soon will it help?
Usually over a few weeks of regular use rather than straight away.
Can I use it with a vaginal moisturiser?
Often yes, and many people do. Ask a pharmacist about timing.
Always read the patient information leaflet supplied with the pack before use.
Medically reviewed and published
This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on Aug 24, 2023, 3:30 pm
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