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At a glance

QUICK SUMMARY

01 Type of medicine

Anti-androgen; progestogen; oral tablet.

02 Generic
03 Active ingredient
04 Effective within
05 Works by

Blocking the effects of androgen hormones, including testosterone, and reducing androgen activity in the body.

06 Side effects

MEDICATION DETAILS

Description

Cyproterone Acetate 50mg Tablets

Cyproterone acetate 50mg is a medicine with anti androgen and progestogenic effects, supplied in packs of 56 tablets. It requires a clinician to assess whether it is suitable for you, to set the dose and schedule, and to review treatment regularly, because it carries important risks that need ongoing monitoring.

How it works

Androgens such as testosterone act by binding to androgen receptors in tissues throughout the body. Cyproterone acetate blocks those receptors, so the hormone circulating cannot produce its usual effect, and it may also reduce how much testosterone the body produces. Depending on the exact licensed product, it may be used for certain androgen dependent conditions.

How to use it

Take the tablets exactly as your clinician has directed. The dose, schedule and duration are set individually and should not be changed or stopped without advice. Attend every monitoring appointment arranged for you, including any blood tests, since these are how problems are picked up before they become serious.

Who it is for

It is for people where a clinician has established a clear indication and judged the benefits to outweigh the risks for their circumstances. Your clinician needs a full picture of your medical history and every other medicine you take before treatment begins.

Safety and when to get advice

Cyproterone acetate is associated with important risks, including liver problems, blood clots, and meningioma where cumulative exposure is higher. Seek urgent medical help for yellowing of the skin or eyes, dark urine, severe abdominal pain, swelling or pain in a leg, chest pain or sudden breathlessness, and contact your clinician about persistent headaches, visual changes, memory problems or seizures. Read the patient information leaflet supplied with your exact product for full information on directions, monitoring and possible side effects. Our UK pharmacy team can answer questions about this product.

Common questions

Why is monitoring needed?
Regular review and blood tests are how liver effects and other risks are detected early.

Can I stop it if I feel fine?
Do not change or stop treatment without speaking to your clinician first.

Does it interact with other medicines?
It can. Tell your clinician and pharmacist about everything you take, including supplements.

Always read the patient information leaflet supplied with the pack before use.

Directions

Take the tablets exactly as prescribed, usually after food and with water. The number of tablets, frequency and duration of treatment depend on the condition being treated. Do not change the dose or stop treatment without speaking to the prescriber.

Ingredients

Active ingredient: Cyproterone acetate 50 mg per tablet. Refer to the packaging and Patient Information Leaflet supplied with the exact manufacturer’s product for the complete list of inactive ingredients.

Side Effects

Possible side effects include tiredness, weight changes, hot flushes, reduced sexual desire, mood changes, breast tenderness, reduced fertility and changes in liver function. Serious effects may include liver injury, blood clots and meningioma. Read the supplied leaflet for the complete list.

Warnings

Do not use this medicine if you currently have or have previously had a meningioma. Treatment may require liver-function tests, blood tests and regular clinical reviews. Seek urgent medical advice for yellowing of the skin or eyes, severe abdominal pain, unusual headaches, vision or hearing changes, leg swelling, chest pain or difficulty breathing.

Medically reviewed and published

  • This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on Jul 30, 2026, 10:00 am

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FAQs

Please read our FAQs page to find out more.

What is Cyproterone Acetate 50 mg used for?

Cyproterone acetate is used for conditions where the effects of androgen hormones, such as testosterone, need to be reduced. The exact licensed indication depends on the product supplied. Some 50 mg products are used in prostate-cancer treatment, while others are licensed to control severe hypersexuality in adult men when other interventions are unsuitable.

How does Cyproterone Acetate work?

Cyproterone acetate blocks androgen receptors, reducing the effects of testosterone and related hormones on the body. Its progestogenic action may also reduce testosterone production.

How should Cyproterone Acetate tablets be taken?

Take the tablets exactly as directed by the prescriber, usually after food and with water. The dose and schedule depend on the condition being treated. Do not take additional tablets or alter the dose without medical advice.

What monitoring may be required during treatment?

The clinician may arrange liver-function tests, blood tests and regular clinical assessments. Monitoring requirements will depend on the dose, treatment duration, medical history and other medicines being taken.

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